Adam Fabriwerk Pvt. Ltd.

CLEANING IN PLACE (CIP) Module is the process used to ensure that, process reactors, vessels and lines are free of organic and inorganic contaminants:

Biopharmaceuticals

• Vaccines

• Human Insulin

• Serums

• Plasma Fractions

• Bacteria and cell cultures

 CIP cycles can be subjected to the following process machinery

• Fermentors

• Blending Vessels

• Media / Harvest / Storage / Filtration Vessels

• Transfer Lines

• Process Equipment

Technical Highlights

• Completely Automated Process Cycles

• On line display of process parameters with P & I of Operating
Systems

• Display of Fault messages

• Supervisory access code prevent unauthorized changes

• Detergent / Acid / Alkali dosing

• On Line pH, Conductivity, TOC Sensing

• CIP is designed in accordance with ASME BPE and EHEDG guidelines

• PLC-based, with Touch Screen MMI and SCADA Packages

Key Benefits:

• Validatable process for Sterilization of process equipment

• Lower Facility Operating Costs

• Minimal dismantling of equipment and piping

• Reduced turnaround time for cleaning

• WFI requirement for cleaning reduced significantly

• Exposure to hazardous activities or entry into tanks, is eliminated

Spray device characteristics

• The cleaning liquid turns the spray head by means of a specially
positioned nozzle

• Rapid repitition impact loosens the dirt and washes it off the tank
surface

• The cleaning effects is optimum at low pressure in small to medium
size tanks

• With increasing pressure, the rotation speed gets higher, while due
to stronger atomization, the reach of the spray gets lower

• Operation at the optimum pressure ensures required cleaning results
and avoids wear of the nozzle

Effective Cleaning Criteria Factors include

• Cleaning Cycle Time

• Cleaning Agent and Temperature

• Concentration and Chemistry of the Cleaning Agent within the circuit

• Degree of Turbulence of the Cleaning Solution

• Characteristics of the surface being cleaned

• Spray Device Selection (Static Dynamic)

Capacity

• CIP Module for Processing Vessels ranging from 50 litres to 30000 litres

Adam Fabriwerk has been delivering quality mixing and processing machinery products to Biopharmaceutical, Pharmaceutical, Cosmetic and Allied Industries.

Our corporate offices are based in Mumbai, India and our manufacturing facility and R&D lab is located at Nashik, approx 200 kms away from Mumbai.

We operate a comprehensive QA system with documentation compliant with FDA requirements and offer tailor made solutions for Customers; adaptable control concepts for different levels of automation and constant innovation make us a key player in the processing machinery industry.